Reid Hoffman is leaving Microsoft’s board to go ‘founder mode’ with startup Manus
TechCrunch·June 5, 2026
Reid Hoffman is leaving Microsoft's board of directors after a decade of service. His departure is driven by a desire to focus on his own startup, Manus, which utilizes artificial intelligence for drug discovery. Hoffman's tenure on Microsoft's board was highly profitable, and he now seeks to dedicate his time to Manus in what he calls "founder mode". His transition marks a new chapter in his career, shifting from a board role to a hands-on entrepreneurial pursuit.
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